Recommended Background Readings for the Laboratory

Barton, L. F., Runnels, H. A., Schell, T. D., Cho, Y., Gibbons, R., Tevethia, S. S., Deepe, G. S., Jr., and Monaco, J. J. (2004). Immune defects in 28-kDa proteasome activator gamma-deficient mice. J Immunol 172, 3948-3954.

Chen, X., Barton, L. F., Chi, Y., Clurman, B. E., and Roberts, J. M. (2007). Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome. Mol Cell 26, 843-852.

Cioce, M., Boulon, S., Matera, A. G., and Lamond, A. I. (2006). UV-induced fragmentation of Cajal bodies. J Cell Biol 175, 401-413.

Groll, M., Bajorek, M., Kohler, A., Moroder, L., Rubin, D. M., Huber, R., Glickman, M. H., and Finley, D. (2000). A gated channel into the proteasome core particle. Nat Struct Biol 7, 1062-1067.

Hagemann, C., Patel, R., and Blank, J. L. (2003). MEKK3 interacts with the PA28 gamma regulatory subunit of the proteasome. Biochem J 373, 71-79.

Li, J., and Rechsteiner, M. (2001). Molecular dissection of the 11S REG (PA28) proteasome activators. Biochimie 83, 373-383.

Li, X., Amazit, L., Long, W., Lonard, D. M., Monaco, J. J., and O'Malley, B. W. (2007). Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway. Mol Cell 26, 831-842.

Li, X., Lonard, D. M., Jung, S. Y., Malovannaya, A., Feng, Q., Qin, J., Tsai, S. Y., Tsai, M. J., and O'Malley, B. W. (2006). The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell 124, 381-392.

Mao, I., Liu, J., Li, X., and Luo, H. (2008). REGgamma, a proteasome activator and beyond? Cell Mol Life Sci 65, 3971-3980.

Murata, S., Kawahara, H., Tohma, S., Yamamoto, K., Kasahara, M., Nabeshima, Y., Tanaka, K., and Chiba, T. (1999). Growth retardation in mice lacking the proteasome activator PA28gamma. J Biol Chem 274, 38211-38215.

Rechsteiner, M., and Hill, C. P. (2005). Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors. Trends Cell Biol 15, 27-33.

Shibatani, T., Carlson, E. J., Larabee, F., McCormack, A. L., Fruh, K., and Skach, W. R. (2006). Global organization and function of mammalian cytosolic proteasome pools: Implications for PA28 and 19S regulatory complexes. Mol Biol Cell 17, 4962-4971.

 Tanaka, K., and Chiba, T. (1998). The proteasome: a protein-destroying machine. Genes Cells 3, 499-510.

Whitby, F. G., Masters, E. I., Kramer, L., Knowlton, J. R., Yao, Y., Wang, C. C., and Hill, C. P. (2000). Structural basis for the activation of 20S proteasomes by 11S regulators. Nature 408, 115-120.

Zannini, L., Buscemi, G., Fontanella, E., Lisanti, S., and Delia, D. (2009). REGgamma/PA28gamma proteasome activator interacts with PML and Chk2 and affects PML nuclear bodies number. Cell Cycle 8.

Zannini, L., Lecis, D., Buscemi, G., Carlessi, L., Gasparini, P., Fontanella, E., Lisanti, S., Barton, L., and Delia, D. (2008). REGgamma proteasome activator is involved in the maintenance of chromosomal stability. Cell Cycle 7, 504-512.

Zhang, Z., and Zhang, R. (2008). Proteasome activator PA28 gamma regulates p53 by enhancing its MDM2-mediated degradation. Embo J 27, 852-864.

Zhou, P. (2006). REGgamma: a shortcut to destruction. Cell 124, 256-257.

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